Summary: In implementation of solutions for achievement of strategic objectives to develop science and technology in closely link with the strategic objectives of socio-economic development, a number of tasks relating to science and technology management in the area of labor and social issues are identified as follows: to be concretize the guidelines and policies of the Party and State, comprehensive reform and consistent organizational reform, innovating scientific management mechanism such as: mechanism on research service order, determining the responsibilities of research agencies, the financial mechanism for researches, assessment of the research quality. This paper aims to provide the overview of administration of scientific activities over time and recommends for betterment